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Nephrology

Looking beyond hypertension: impact of RAS blockade in patients with type 2 diabetes and minority populations

Prakash C. Deedwania, MD, FACC, FACP, FAHA

 
African American, Hispanic, South Asian, and Pima Indian populations are at high risk for cardiovascular mortality and morbidity, partly owing to greater prevalence of diabetes and obesity. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are the treatment of choice for patients with diabetes at high risk for cardiovascular events. Early reports suggest dual renin-angiotensin system blockade is as effective as monotherapy in high-risk patients; further studies will determine if it increases cardioprotective effects in patients with chronic kidney disease, diabetes, and heart failure.

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